Assessment of testicular toxicity in laboratory animals

نویسندگان

  • Ralph Heywood
  • Ronald W. James
چکیده

The currently available methods of assessing testicular toxicity and fertility are discussed. Compounds inducing testicular atrophy mainly affect the seminiferous epithelium, with progressive loss of spermatozoa, spermatids, spermatocytes, and spermatogonia. Quantitative histometric analysis of spermatogenesis, together with hormone assays, could be used to advantage in defining the underlying mechanisms of toxicity.

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عنوان ژورنال:
  • Environmental Health Perspectives

دوره 24  شماره 

صفحات  -

تاریخ انتشار 1978